Penn’s Experimental Gene Therapy Saves Night Vision in Dogs, Paving the Way for Human Tests

In 1990, scientists discovered a genetic mutation that turns an important light-sensing protein in the retina into a toxin that steadily destroys the ability to see in low light.

Many similar mutations have been identified since then, but there is still no way to treat or prevent the loss of night vision.

Now, University of Pennsylvania researchers have used gene therapy to do just that in a canine version of the inherited retinal disorder, according to a report in the Philadelphia Inquirer.

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