Iantrek Announces First Commercial Cases of C.Rex Micro-Interventional System for Trabecular Outflow Enhancement
Iantrek announced the completion of the first commercial cases utilizing its C.Rex micro-interventional system for canal outflow enhancement in glaucoma surgery. Iantrek said the milestone marks the beginning of the company's pre-launch activities for the C.Rex technology.
C.Rex is an ophthalmic surgical system designed for canal outflow gonio-intervention, and is the only FDA-registered minimally invasive glaucoma surgery (MIGS) technology capable of excisional circumferential trabeculorhexis and dual wall canal intervention. The system leverages Nitinol filament technology, incorporating flexible micro-instrumentation with memory-shaped super-elasticity to achieve a full 360-degree excisional, single- or dual-wall canalotomy. According to Iantrek, u nlike conventional intraocular interventions such as micro-stents, lasers, and non-implantable devices that target limited segments of the canal inner wall, the C.Rex portfolio uniquely enables fully titratable 180- to 360-degree comprehensive intervention.
“All conventional approaches have focused on the trabecular meshwork and the inner canal wall. We have shown empirically and presented our study at ARVO that dual canal intervention can lead to incremental outflow enhancement over single inner wall goniotomy," Carol Toris, Professor at the University of Nebraska Medical Center, said in a company news release. "Iantrek’s approach is uniquely original as it is able to address outflow resistance in the entire canal.”
Arkadidy Yadgarov, MD, of OMNI Eye Services in Atlanta, was the first surgeon in the United States to utilize the technology.
“There are a lot of trabecular technologies, but this is an interventional breakthrough in non-implantable trabecular outflow surgery," Dr. Yadgarov said. "It is one of the most surgically intuitive MIGS technologies, and the only goniotomy system to enable surgical intervention on the entire canal, not just segmentally. The C.Rex offers circumferential excisional goniotomy which is guided, continuous, comprehensive and can reduce resistance in the outer wall.”