EssilorLuxottica Unveils 4-Year Clinical Trial Results of its Essilor Stellest Lens at

EssilorLuxottica presented the 4-year clinical trial results of its Essilor Stellest lens for myopia control at the 2023 ARVO annual meeting in New Orleans. The findings show that Essilor Stellest lenses continue to exhibit strong efficacy in slowing myopia progression and axial eye elongation in children in the fourth year, according to a company news release.

The clinical trial, which began in 2018, was conducted at the Eye Hospital of Wenzhou Medical University in Wenzhou, China. The study assessed the 4-year increase of myopia and axial eye length of children who wore spectacle lenses with highly aspherical lenslets (HAL). Essilor Stellest lenses are based on the optical design of HAL lenses. The key findings from the study include:

• HAL lenses saved more than one and a quarter dioptres of myopia on average over 4 years, demonstrating evidence of their effectiveness in slowing down myopia progression in children in the fourth year
• Myopia progression and axial eye elongation in children wearing HAL lenses was slower compared to a modelled control single vision lens group[1] , indicating sustained myopia control efficacy of the lenses in the fourth year
• HAL lenses remain effective in slowing myopia progression and axial eye elongation in older children (11-16 y.o.) in the fourth year.

The 4-year results were presented by Dr. Björn Drobe from EssilorLuxottica’s R&D team.

Dr. Yee Ling Wong from the R&D team presented findings from a study that evaluated the eye growth of children wearing spectacle lenses with aspherical lenslets and with single-vision lenses in comparison to eye growth patterns in non-myopic children in Wenzhou, China. These findings concluded that the eye growth pattern in 9 out of 10 children wearing HAL lenses fulltime was similar or slower than that of non-myopic children, after 2 years.

The release of the 4-year data follows the recent publication of the 3-year clinical trial findings in the journal American Journal of Ophthalmology, which also highlights evidence of continued myopia control efficacy of the lens in slowing down myopia progression in children over 3 years. When children switched to HAL lenses in the third year after 2 years of wearing single vision lenses, myopia progression and axial eye elongation decreased significantly, compared to children wearing single vision lenses.

References

1 Based on Wright Shamp, Noel A Brennan, Mark A Bullimore, Xu Cheng, Elizabeth Maynes; Influence of Age and Race on Axial Elongation in Myopic Children. Invest. Ophthalmol. Vis. Sci. 2022;63(7):257 – A0111.