Centricity: Study Finds Zepto Precision Pulse Capsulotomy Offers Advantages Over Manual Capsulorhexis in Treating White Cataracts

Centricity Vision announced that a new study, published in the Journal of Cataract & Refractive Surgery (JCRS), demonstrated the superiority of its Precision Pulse Capsulotomy (PPC) technology over Continuous Curvilinear Capsulorhexis (CCC or manual capsulorhexis) for capsulotomy creation in white cataracts.

The company-sponsored study revealed that the use of PPC has advantages over CCC, including:

• Reliable creation of complete, consistently round capsulotomies without tags or tears
• Highly effective method to quickly decompress and neutralize any potential intralenticular pressure
• No "Argentinian flag" sign, a common complication when performing capsulorhexis in pressurized intumescent cataracts stained with trypan blue 
• Elimination of trypan blue capsular staining and high molecular weight cohesive ophthalmic viscosurgical device (OVD) 
• Reduced overall procedural time of approximately 1 minute on average
• IOL implantation with 360-degree capsular overlap in all cases

The new study supports the use of Zepto as a valuable tool for surgeons seeking enhanced precision for IOL placement and capsulotomy creation, reduced procedural time, and improved resource utilization, according to Centricity. 

"Surgical treatment of white cataracts has a high rate of complications, with peer-reviewed literature showing white cataracts to be the biggest risk factor for a dropped nucleus," study co-author Cristos Ifantides, MD, MBA, said in a company news release. "I rely on Zepto's Precision Pulse technology as a safe and highly effective method to create consistent capsulotomies in patients with both intumescent and non-intumescent white cataracts. Zepto can turn these complex cases into routine surgeries and can cut down on surgical time." 

The study included a retrospective analysis of surgical case records and videos from a single surgeon. It compared 15 cases of white cataract (10 intumescent, 5 non-intumescent) performed using CCC with 20 cases (9 intumescent, 11 non-intumescent) performed using PPC.

Designed to enhance the precision and efficiency of cataract surgery, the Zepto IOL Positioning System is the first and only device that creates an instantaneous capsulotomy for 360-degree IOL overlap and improved outcomes, according to Centricity Vision. 

Disclosures: Dr. Ifantides has received research support from and is a consultant for Centricity Vision, Inc.