Allegro to Present Results of Its ALG-1007 Ex-US Trial for Dry Eye Disease at ASCRS

Following last week’s news that the company is expanding its pipeline into dry eye and has created a new Cornea Scientific Advisory Board (Cornea SAB), Allegro Ophthalmics announced that the results of its ALG-1007 ex-U.S. proof-of-concept clinical trial for the treatment of dry eye disease (DED) will be presented during the 2019 American Society of Cataract and Refractive Surgery and American Society of Ophthalmic Administrators (ASCRS•ASOA) annual meeting being held May 3-7 in San Diego.

On Thursday, May 2, Allegro’s President and CEO Vicken Karageozian, MD, will provide an overview on the company’s vision moving forward into other ocular indications at the Ophthalmology Innovation Summit (OIS). Then on Monday, May 6, Eric D. Donnenfeld, MD, will present full study results of the ALG-1007 ex-U.S. proof-of-concept clinical trial for DED at ASCRS•ASOA.

The expansion into front-of-the-eye indications bolsters Allegro’s existing anti-integrin portfolio, which includes risuteganib (Luminate), currently being developed for diabetic macular edema (DME) and intermediate dry age-related macular degeneration (intermediate dry AMD). Preclinical and clinical findings of risuteganib convinced the company that it could develop a new anti-integrin compound to treat DED.

“Allegro is excited to share, for the first time, our ex-U.S. proof-of-concept data with the clinical community at ASCRS and OIS,” Dr. Karageozian said in a company news release. “Allegro is continuously exploring new ways to apply our anti-integrin portfolio to help improve patients’ vision, and ALG-1007 represents our first exploratory drug for the potential treatment of dry eye, a disease that adversely affects millions of Americans.”

The corporate and scientific presentations are scheduled as follows:

Thursday, May 2: 9:45-9:51 AM
Ophthalmology Innovation Summit, Hilton San Diego Bayfront
Addressing the Unmet Need of Ocular Diseases with a Novel Anti-Integrin Portfolio. Vicken Karageozian, M.D.

Monday, May 6: 1:45-1:50 AM
San Diego Convention Center, Room 1B
A Pilot Study to Evaluate the Safety and Exploratory Efficacy of ALG-1007 Topical Ophthalmic Solution for the Treatment of Dry Eye Disease. Eric D. Donnenfeld, M.D.