Alcon Announces its Largest Scientific Presence at ASCRS 2023 and Expands Image-Guided Connectivity

Alcon announced its surgical ophthalmic presence at the American Society of Cataract and Refractive Surgery (ASCRS) 2023 annual meeting, taking place May 5-8 in San Diego, and stated that its innovations will be featured in more studies than ever in its history.[1] Alcon ASCRS event information and registration is available at MyAlconatASCRS.com.

“The pace of innovation happening across eye care is extraordinary, and as the industry leader, we are excited to be leading the charge at ASCRS 2023,” said Sergio Duplan, President, North America at Alcon. “As a testament to our commitment to groundbreaking research and innovation, we’re excited to have a significant presence at ASCRS that underscores how our products are changing the lives of patients and surgeons alike.”

Clinical studies continue to demonstrate benefits of Clareon Collection of IOLs. A study from Micheletti et. al. evaluates a head-to-head comparison of distance and intermediate vision of Clareon monofocal IOL and Tecnis Eyhance monofocal IOL. The study concludes that Clareon monofocal IOLs provided excellent distance and comparable intermediate vision that was noninferior to Tecnis Eyhance monofocal IOLs.[2] Dr. J. Morgan Micheletti will be presenting his full findings on May 6 from 11:09-11:14 a.m., during the “Cataract IOLs-Monofocal/Extended Depth of Focus II session,” Upper Level, Room 4.2

Additional data on Alcon IOLs will be presented, including:[9-10]

• Prospective Analysis of PanOptix Satisfaction and Higher Order Aberrations in Patients with Prior Myopic Laser Vision Correction, Presented by Dr. Brett H. Mueller II (May 6, 9:05-9:10 a.m.)
• Evaluation of Refractive Stability and Binocular Visual Acuity in a New Monofocal Hydrophobic Acrylic Intraocular Lens, Presented by Dr. Clayton Blehm (May 6, 1:45-1:50)

Argos Biometer is now connected to NGENUITY 1.5, enabling surgeons to conduct 3D digital image-guided cataract surgery, increasing workflow efficiency and precision.[3-8] ARGOS biometry measurements and images can now be imported to NGENUITY 1.5, enabling cataract surgeons to precisely overlay incision location, capsulorhexis, IOL centration and toric alignment. Now available in the U.S., the open-platform NGENUITY 1.5 offers superior visualization and includes usability, color, contrast and magnification enhancements.[4] NGENUITY 1.5 will be featured at Alcon Booth #2111.

Data will be presented at ASCRS demonstrating how surgeons benefit from using ARGOS and NGENUITY in their practices:[11-13]

• Comparison Trial Evaluating Axial Lengths and Predicted Spherical Equivalents of Three Biometers, Presented by Dr. Sam Multack (Electronic Poster)
• Comparing Refractive Outcomes of a Swept-Source Optical Coherence Tomography Biometer and an Optical Low Coherence Reflectometry Biometer, Presented by Dr. Clayton G. Blehm (May 6, 3:35-3:40 p.m.)
• Development of Phototoxic Maculopathy as a Function of Coaxial Illumination Intensity in Diabetic Patients at the Time of Cataract Surgery, Presented by Lopa S Shah (May 6, 4:20-4:25 p.m.)

New data on the Hydrus Microstent reinforce significant IOP reduction in glaucoma patients with higher baseline IOP compared to those who receive cataract surgery alone.[14] Dr. Cathleen McCabe will present these new findings from a randomized, controlled clinical trial on May 6 from 2:27-2:32 p.m. These new findings are derived from the HORIZON 5-year trial results, which had previously demonstrated that the Hydrus Microstent offers long-term glaucoma medication reduction and reduction of IOP.[14] Surgeons can learn more about the Hydrus Microstent and Alcon pharmaceutical glaucoma products at booth #2111.

Additional data supporting Alcon innovation in cataract glaucoma patients include:[15-16]

• Clinical Outcomes of a Non-Diffractive Extended Depth-of-Focus IOL in Eyes with Glaucoma, Presented by Dr. Tanner J. Ferguson (May 6, 8:00-8:05 a.m.)
• Visual Performance of a Trifocal IOL in Subjects with Open-Angle Glaucoma Undergoing Concurrent Minimally Invasive Glaucoma Surgery, Presented by Dr. Steven D. Vold (May 6, 1:50-1:55 p.m.)

Evidence supports that phacoemulsification in cataract surgery with Centurion Vision System with Active Sentry allows surgeons to operate at a more physiological IOP with excellent anterior chamber stability and surgical efficiency.[17] A study by Vaishali Vasavada showed that rise of IOP to baseline following occlusion break response was faster with Active Sentry handpiece as compared to traditional handpiece when using the Centurion Vision System.[17] The full study will be presented on Sunday, May 7 at 1:45 pm.

Additional data on Centurion with Active Sentry include:[18-20]

• Improved Surgical Times Using Active Sentry Hand Piece on the Centurion Cataract System, a Randomized Controlled Trial, Presented by Julio Echegoyen, MD, ABO (On-Demand Electronic Poster, May 5, 8:05-8:10 p.m.)
• Surge and Capsule Dynamics during Phacoemulsification using an Adjustable Compliance Mechanical Eye Model, Presented by Dr. Jaime Zacharias (May 7, 4:45-4:50 p.m.)
• Evaluation of Early Changes of the Anterior Vitreous Interface after Cataract Surgery, Using Low-Pressure Settings Determined by OCT, Presented by Hugo A. Scarfone, MD; Emilia Carolina C. Rodriguez, MD (May 6, 8:05-8:10 a.m.)

Additional educational opportunities and experiences for surgeons will be available at the Alcon booth #2111. For information on Alcon events and news at ASCRS, please visit MyAlconatASCRS.com.

References

1. Alcon Data on File.
2. Micheletti JM, Duncan N, Hall B. Head-to-Head Comparison of Intermediate Vision of Two Monofocal Intraocular Lenses. Presented at the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 5-8, 2023; San Diego, CA, USA.
3. NGENUITY^® 1.5 3D Visualization System User Manual.
4. Berquet F, Henry A, Barbe C, et al. Comparing heads-up versus binocular microscope visualization systems in anterior and posterior segment surgeries: a retrospective study. Ophthalmologica. 2020;243(5):347-354.
5. Alcon Data on File.
6. Mouro-Coelho N, Nascimento J, Henriques J, Medeiros MD. Three-dimensional display systems in ophthalmic surgery – a review. European Ophthalmic Review. 2019;13(1):31-36.
7. Tamaoki A, Kojima T, Hasegawa A, et al. Clinical evaluation of a new swept-source optical coherence biometer that uses individual refractive indices to measure axial length in cataract patients. Ophthalmic Res. 2019;19:1-13.
8. Shammas HJ, Ortiz S, Shammas MC, et al. Biometry measurements using a new large-coherence-length swept-source optical coherence tomographer. J Cataract Refract Surg. 2016;42:50-61.
9. Mueller BH, Saenz B, Parkhurst GD, Welburn KR. Prospective Analysis of Panoptix Satisfaction and Higher Order Aberrations in Patients with Prior Myopic Laser Vision Correction. Presented at the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 5-8, 2023; San Diego, CA, USA.
10. Blehm Clayton G. Evaluation of Refractive Stability and Binocular Visual Acuity in a New Monofocal Hydrophobic Acrylic Intraocular Lens. Presented at the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 5-8, 2023; San Diego, CA, USA.
11. Multack Sam. Comparison Trial Evaluating Axial Lengths and Predicted Spherical Equivalents of Three Biometers. Presented at the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 5-8, 2023; San Diego, CA, USA.
12. Blehm Clayton G. Comparing Refractive Outcomes of a Swept-Source Optical Coherence Tomography Biometer and an Optical Low Coherence Reflectometry Biometer. Presented at the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 5-8, 2023; San Diego, CA, USA.
13. Lopa SS, Rosenberg E. Development of Phototoxic Maculopathy as a Function of Coaxial Illumination Intensity in Diabetic Patients at the Time of Cataract Surgery. Presented at the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 5-8, 2023; San Diego, CA, USA.
14. McCabe Cathleen M. Increase in High Level IOP Reduction with a Schlemm’s Canal Microstent: Outcomes from a Randomized, Controlled Clinical Trial. Presented at the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 5-8, 2023; San Diego, CA, USA.
15. Ferguson TJ, Wilson CW, Shafer BM, Berdahl JP, et al. Clinical Outcomes of a Non-Diffractive Extended Depth-of-Focus IOL in Eyes with Glaucoma. Presented at the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 5-8, 2023; San Diego, CA, USA.
16. Vold SD, McFarland MR. Visual Performance of a Trifocal IOL in Subjects with Open-Angle Glaucoma Undergoing Concurrent Minimally Invasive Glaucoma Surgery. Presented at the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 5-8, 2023; San Diego, CA, USA.
17. Vasavada V, et. al. Comparison of Intraoperative Performance, Intraocular Pressure and Postoperative Outcomes during Cataract Surgery with Three Fluidic Systems. Presented at the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 5-8, 2023; San Diego, CA, USA.
18. Echegoyen Julio. Improved Surgical Times Utilizing Fluidic Analysis at the Eye Level, A Randomized Controlled Trial. Presented at the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 5-8, 2023; San Diego, CA, USA.
19. Zacharias J, Berthet N, Orellana D. Surge and Capsule Dynamics during Phacoemulsification using an Adjustable Compliance Mechanical Eye Mode. Presented at the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 5-8, 2023; San Diego, CA, USA.
20. Scarfone HA, Rodriguez Emilia CC. Evaluation of Early Changes of the Anterior Vitreous Interface After Cataract Surgery, Using Low-Pressure Settings Determined By OCT. Presented at the American Society of Cataract and Refractive Surgery (ASCRS) Annual Meeting; May 5-8, 2023; San Diego, CA, USA.