What's new on the glaucoma front?

Two words: biodegradable implants. The FDA has accepted Allergan's new drug application for Bimatoprost Sustained-Release (SR).

What is it?

It's called Bimatoprost SR and it's a biodegradable implant that dispenses bimatoprost (aka Lumigan) for at least 4 months. It's injected into the anterior chamber and is visible in the inferior iridocorneal angle, where it slowly dispenses medication and degrades.

Why could this be a big deal?

Because if approved, it would be a first-in-class, sustained-release, biodegradable implant for the reduction of IOP.

How much IOP reduction are we talking?

In phase 3 trials, Bimatoprost SR reduced IOP by 30% over 12 weeks, which is similar to the effect of topical prostaglandins.

When could this be a thing?

The FDA will make an announcement in the first half of 2020.


Transitions Signature Gen 8 is out.
How is this different from the previous generations?

Faster adaptation time. These lenses "activate up to 30% faster and fade back to clear up to 3 minutes faster."
Your patient may see the new advertised promo for these lenses—check out the details here. And to see this lens in action, watch this unboxing video.


Can I go blind from wearing my contacts in the shower?

NBC news reported on a case published in the New England Journal of Medicine last week.

Here is the background:

The case details a patient who wore monthly lenses, even while swimming and showering. She presented to an eye clinic after 2 months of intermittent pain and was diagnosed with acanthamoeba. She ended up needing a partial-thickness corneal transplant (DALK) 1 year later, and her resulting best corrected acuity was 20/80.
Refer to the photo for full effect.


Can I get rid of all blue light?

According to the Daily Mail, Elon Musk's girlfriend underwent an "experimental surgery to eliminate all blue light from her vision by removing the top film of her eyeball and replacing it with an orange layer that she made in a lab." Pics or it didn't happen. (via)